Table 1 Patient characteristics
Dormant, n (%) | Resistant, n (%) | Total, n | p valuea | |
|---|---|---|---|---|
Total no. of patients | 42 | 20 | 62 | |
Total no. of samples | 111 | 56 | 167 | |
Age at diagnosis | ||||
Mean | 75 | 72 | ||
Range | 53–87 | 56–89 | ||
Tumour grade | 0.39 | |||
1 | 6 (14.3) | 1 (5.0) | 7 | |
2 | 27 (64.3) | 10 (50.0) | 37 | |
3 | 8 (19.0) | 6 (30.0) | 14 | |
NA | 1 (2.4) | 3 (15.0) | 4 | |
Tumour size | 0.71 | |||
T1 | 5 (11.9) | 4 (20.0) | 9 | |
T2 | 19 (45.2) | 9 (45.0) | 28 | |
T3 | 2 (4.8) | 2 (10.0) | 4 | |
T4 | 11 (26.2) | 4 (20.0) | 15 | |
NA | 5 (11.9) | 1 (5.0) | 6 | |
Nodal status | 0.36 | |||
N0 | 27 (64.3) | 11 (55.0) | 38 | |
N1 | 8 (19.0) | 7 (35.0) | 15 | |
N2 | 1 (2.4) | 1 (5.0) | 2 | |
N3 | 1 (2.4) | 0 | 1 | |
NX | 1 (2.4) | 0 | 1 | |
NA | 4 (9.5) | 1 (5.0) | 5 | |
Metastasis status | 1.00 | |||
M0 | 34 (80.9) | 18 (90.0) | 56 | |
M1 | 2 (4.8) | 0 | 2 | |
MX | 1 (2.4) | 1 (5.0) | 2 | |
NA | 5 (11.9) | 1 (5.0) | 6 | |
ER score (Allred) | 0.18 | |||
6 | 1 (2.4) | 0 | 1 | |
7 | 6 (14.3) | 6 (30.0) | 12 | |
8 | 35 (83.3) | 14 (70.0) | 49 | |
HER status | 0.69 | |||
Negative | 35 (83.3) | 12 (60.0) | 47 | |
Positive | 6 (14.3) | 3 (15.0) | 9 | |
NA | 1 (2.4) | 5 (25.0) | 6 | |
Histological type | 0.73 | |||
IDC (no special type) | 18 (42.9) | 6 (30) | 24 | |
ILC | 8 (19.0) | 4 (20) | 12 | |
Mucinous | 1 (2.4) | 0 | 1 | |
NA | 15 (35.7) | 10 (50) | 25 | |
Molecular subtypeb | 1.00 | |||
Luminal A | 21 (50.0) | 9 (45.0) | 30 | |
Luminal B | 20 (47.6) | 9 (45.0) | 29 | |
HER2 enriched | 0 | 1 (5.0) | 1 | |
Basal-like | 0 | 0 | 0 | |
Normal-like | 0 | 0 | 0 | |
NA | 1 (2.4) | 1 (5.0) | 2 | |