Fig. 6
From: Impact of obesity on breast cancer recurrence and minimal residual disease
Diet-induced obesity is associated with accelerated mammary tumor recurrence (median recurrence-free survival [RFS]: high-fat diet [HFD]-Obese: 53.0 days vs. HFD-lean: 87.0 days vs. low-fat diet [LFD]: 80.0 days, p < 0.001) and increased recurrence risk (relative to HFD-Lean: HR 2.52, 95% CI 1.52–4.16; relative to LFD: HR 2.27, 95% CI 1.42–3.63). There was no significant difference in RFS between the two lean cohorts (p = 0.647)