Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas

Breast Cancer Research

Table 2 Representative SNPs and association statistics from each of four different SNP clusters/regions that are genome-wide significant

SNP/risk allele	Allele frequency	Position (BP, Hg19)	Odds ratio (95% CI)	P value	Conditional OR* P value	Joint OR** P value
rs140068132-G	0.0933	6:151954834	0.58 (0.50–0.66)	4.4 × 10^− 15		0.61 (0.53–0.71) 6.8 × 10^− 12
rs851980-C	0.255	6:152027955	1.28 (1.18–1.35)	5.2 × 10⁻¹⁰	1.22 (1.12–1.32) 1.0 × 10^− 6	1.19 (1.10–1.28) 3 × 10^− 6
rs3778609-T	0.192	6:152133187	0.76 (0.69–0.83)	6.0 × 10⁻⁹	0.84 (0.76–0.93) 6.5 × 10^− 4	0.86 (0.78–0.95) 0.0035

ISSN: 1465-542X