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Table 2 Pearson’s correlation coefficients of mammographic measuresa with BMIa and with log NDV

From: Adjusting for BMI in analyses of volumetric mammographic density and breast cancer risk

  Adjusted log BMI Adjusted log NDV
UK case control study controls onlyb Norwegian cohort study full cohortc UK case control study controls onlyb Norwegian cohort study full cohortc
Adjusted log NDV 0.74 0.72
Adjusted log %MD −0.66 −0.57 −0.80 −0.72
Adjusted log DV 0.33 0.25 0.57 0.43
  1. Abbreviations: BMI body mass index, DV volume of mammographically dense tissue, NDV volume of mammographically non-dense tissue, %MD percent mammographic density
  2. DV, NDV and %MD averaged over the cranio-caudal and mediolateral-oblique views from the left and right breasts
  3. aAll mammographic features as well as BMI were regressed on age at mammogram, parity and menopausal status and the residuals from these regressions were used to calculate the correlation coefficients and referred to as “adjusted” measures
  4. bn = 646 (women with missing BMI, age, parity, menopausal status or mammographic measurements were excluded and one woman with a BMI greater than 60 was also excluded)
  5. cn = 51,427 (women with missing BMI, age, parity, menopausal status or mammographic measurements were excluded or BMI greater than 60 were excluded)
  6. P <0.0001 in all cases