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Table 1 Clinicopathological characteristics of cohorts A and triple-negative breast cancer cohort B

From: CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

Parameter

Cohort A

Cohort B (TNBC)

N (%)

N (%)

All patients

398

156

Age, years

  <50

124 (31.2)

72 (46.15)

  ≥50

257 (64.6)

80 (50.1)

 Unknown

17 (4.3)

4 (2.56)

Nodal status

 Positive

78 (19.6)

15 (9.6)

 Negative

203 (51.0)

39 (25)

 Unknown

117 (29.4)

104 (66.6)

Tumor size

  <2 cm

217 (54.5)

44 (28.2)

 2–5 cm

73 (17.3)

74 (47.43)

 Unknown

108 (27)

38 (24.35)

Grade

 1–2

97 (24.37)

45 (28.84)

 3

103 (25.87)

78 (50.00)

 NA/Unknown

198 (49.7)

32 (2)

ERα

 Positive (1–3)

264 (66.3)

 

 Negative (0)

89 (22.3)

 

 Unknown

45 (11.3)

 

HER2

 Positive (3+)

20 (5)

 

 Negative (0–1+)

272 (68.3)

 

 Unknown/Equivocal

106 (26.6)

 

Adjuvant treatment

 Hormonal only

93 (23.4)

 

 Chemotherapy only

72 (18.1)

 

 Hormonal+Chemo

48 (12.1)

 

 None

89 (22.4)

 

 Unknown

96 (24.1)

 

Follow-up (m)

 Median (range)

139 (3–385)

52 (4–231)

  1. Abbreviations: ERα estrogen receptor alpha, NA not available, TNBC triple-negative breast cancer