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Fig. 4 | Breast Cancer Research

Fig. 4

From: CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

Fig. 4

Comparison of AQUA protein with METABRIC mRNA expression data. AQUA protein detection and Spearman correlation of tumor-associated macrophage (TAM) biomarker quantitative immunofluorescence (QIF) scores in cohort a (upper panel, a–c) and triple-negative breast cancer (TNBC) cohort B (middle panel, d–f). a Correlation of matrix metalloproteinase 9 (MMP-9) and CD163. b Correlation of MMP-9 and CD68. c Correlation of CD163 and CD68. d Correlation of MMP-9 and CD163. e Correlation of MMP-9 and CD68. f Correlation of CD163 and CD68. At the lower panel correlations of TAM biomarkers, mRNA z-scores from the METABRIC study are shown. g Correlation of MMP-9 and CD163 mRNA. h Correlation of MMP-9 and CD68 mRNA. i Correlation of CD163 and CD68 mRNA. Abbreviation: AU arbitrary units of fluorescence

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Breast Cancer Research

ISSN: 1465-542X

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