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Table 4 Complete blood counts in patients with circulating tumor cells

From: Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer

  No CTC (n = 39) CTC (n = 34) P value Estimate (95% CI)
CA 15-3, mean (SD) 223.71 (384.68) 1084.15 (4136.87) 0.658 6.7 (− 19.2, 87.6)
Alkaline phosphatase, mean (SD) 105.47 (103.98) 198.15 (365.58) 0.401 6 (− 12, 27)
Calcium (korr), mean (SD) 2.34 (0.15) 2.32 (0.25) 0.145 − 0.06 (− 0.13, 0.02)
CRP, mean (SD) 31.92 (47.56) 26.87 (47.69) 0.982 0 (− 8.8, 3.8)
LDH, mean (SD) 281.61 (118.18) 300.15 (228.57) 0.772 − 5 (− 36, 23)
RBC, 1012/L, mean (SD) 4.37 (0.56) 3.85 (0.77) 0.019 − 0.42 (− 0.8, − 0.08)
HGB, g/L, mean (SD) 130.14 (19.85) 118.15 (24.11) 0.051 − 11 (− 21, 0)
HCT, L/L, mean (SD) 0.38 (0.06) 0.35 (0.06) 0.053 − 0.03 (− 0.06, 0)
MCV, fl, mean (SD) 87.46 (5.68) 89.73 (5.26) 0.227 2 (− 1, 4)
MCH, pg, mean (SD) 29.62 (2.52) 30.66 (1.96) 0.157 0.8 (− 0.3, 1.8)
MCHC, g/L, mean (SD) 339.03 (13.98) 341.19 (12.79) 0.667 2 (− 6, 8)
WBC, 109/L, mean (SD) 7.35 (2.13) 7.24 (3.53) 0.334 − 0.6 (− 1.88, 0.81)
Neutrophils, 109/L, mean (SD) 5.33 (1.87) 5.12 (2.87) 0.239 − 0.63 (− 1.65, 0.56)
Lymphocytes, 109/L, mean (SD) 1.37 (0.67) 1.41 (0.85) 0.941 − 0.02 (− 0.38, 0.38)
Monocytes, 109/L, mean (SD) 0.42 (0.12) 0.44 (0.2) 0.843 − 0.01 (− 0.08, 0.07)
Eosinophils, 109/L, mean (SD) 0.16 (0.18) 0.17 (0.12) 0.423 0.02 (− 0.03, 0.09)
Basophils, 109/L, mean (SD) 0.04 (0.07) 0.04 (0.03) 0.256 0.01 (− 0.01, 0.02)
LUC, 109/L, mean (SD) 0.15 (0.22) 0.12 (0.08) 0.912 0 (− 0.03, 0.02)
PLT, 109/L, mean (SD) 289.92 (139.86) 249.93 (91.52) 0.277 − 30 (− 84, 24)
MPV, fl, mean (SD) 8.2 (1.51) 8.68 (1.52) 0.109 0 (0–1)
  1. Abbreviations: CA 15-3 Cancer antigen 15-3, CRP C-reactive protein, HCT Hematocrit, HGB Hemoglobin, LDH Lactate dehydrogenase, LUC Large unstained cells, MCH Mean corpuscular hemoglobin, MCHC Mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, MPV Mean platelet volume, PLT Platelets, RBC Red blood cells, WBC White blood cells
  2. The table shows complete blood counts in patients with and without circulating tumor cells (CTCs).