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Table 3 Comparison of breast cancer-specific quality of life between exercise and usual care groups

From: Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial

  Baseline Post-intervention 3-month follow-up Between-group difference post-intervention
Mean (SD) Mean (SD) P valuea Mean (SD) P valueb Mean (95% CI) P valuec
Physical well-being
 Exercise 19.2 (3.1) 23.2 (3.0) < 0.001 23.1 (3.2) < 0.001 3.9 (7.2 to 1.7) 0.003
 Usual care 19.1 (3.4) 19.1 (3.5) 0.74 – –
Social well-being
 Exercise 19.7 (3.0) 23.0 (3.2) < 0.001 23.0 (3.0) < 0.001 3.3 (6.9 to 1.1) 0.005
 Usual care 19.6 (3.1) 19.5 (3.0) 0.81 – –
Emotional well-being
 Exercise 18.4 (2.6) 20.1 (3.1) 0.01 20.1 (3.5) 0.01 1.7 (3.4 to 0.8) 0.01
 Usual care 18.3 (2.5) 18.2 (2.7) 0.75 – –
Functional well-being
 Exercise 19.9 (3.4) 22.0 (3.2) 0.01 21.9 (3.1) 0.01 2.0 (4.2 to 0.6) 0.01
 Usual care 20.0 (3.6) 19.9 (3.3) 0.83 – –
Additional concerns
 Exercise 21.1 (4.7) 24.7 (4.1) 0.002 24.0 (4.5) 0.001 3.6 (7.7 to 2.0) 0.002
 Usual care 21.7 (4.4) 19.6 (10.4) 0.43 – –
FACT-General
 Exercise 77.2 (9.0) 88.3 (9.9) < 0.001 88.1 (9.2) < 0.001 11.1 (16.4 to 7.7) < 0.001
 Usual care 77.0 (9.1) 76.7 (9.0) 0.54 – –
FACT-Breast
 Exercise 98.3 (14.1) 113.0 (13.0) < 0.001 112.1 (13.2) < 0.001 14.7 (18.2 to 9.7) < 0.001
 Usual care 98.7 (14.4) 96.3 (14.5) 0.44 – –
Trial outcome index
 Exercise 60.2 (7.3) 69.9 (7.5) < 0.001 69.0 (7.7) < 0.001 8.8 (15.3 to 4.3) < 0.001
 Usual care 60.8 (7.5) 58.6 (7.4) 0.64 – –
  1. Abbreviations: SD standard deviation, CI confidence interval, FACT Functional Assessment of Cancer Therapy
  2. aP value for repeated measures ANOVA comparing changes in the exercise group from baseline to post-intervention, and in the usual care group from baseline to post-intervention
  3. bP value for repeated measures ANOVA comparing changes in the exercise group from baseline to 3-month follow-up
  4. cP value for mixed model analysis comparing changes between the exercise and usual care group from baseline to post-intervention
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