| |
Baseline
|
Post-intervention
|
3-month follow-up
|
Between-group difference post-intervention
|
|---|
|
Mean (SD)
|
Mean (SD)
|
P valuea
|
Mean (SD)
|
P valueb
|
Mean (95% CI)
|
P valuec
|
|---|
|
Physical well-being
|
|
Exercise
|
19.2 (3.1)
|
23.2 (3.0)
|
< 0.001
|
23.1 (3.2)
|
< 0.001
|
3.9 (7.2 to 1.7)
|
0.003
|
|
Usual care
|
19.1 (3.4)
|
19.1 (3.5)
|
0.74
|
–
|
–
|
|
Social well-being
|
|
Exercise
|
19.7 (3.0)
|
23.0 (3.2)
|
< 0.001
|
23.0 (3.0)
|
< 0.001
|
3.3 (6.9 to 1.1)
|
0.005
|
|
Usual care
|
19.6 (3.1)
|
19.5 (3.0)
|
0.81
|
–
|
–
|
|
Emotional well-being
|
|
Exercise
|
18.4 (2.6)
|
20.1 (3.1)
|
0.01
|
20.1 (3.5)
|
0.01
|
1.7 (3.4 to 0.8)
|
0.01
|
|
Usual care
|
18.3 (2.5)
|
18.2 (2.7)
|
0.75
|
–
|
–
|
|
Functional well-being
|
|
Exercise
|
19.9 (3.4)
|
22.0 (3.2)
|
0.01
|
21.9 (3.1)
|
0.01
|
2.0 (4.2 to 0.6)
|
0.01
|
|
Usual care
|
20.0 (3.6)
|
19.9 (3.3)
|
0.83
|
–
|
–
|
|
Additional concerns
|
|
Exercise
|
21.1 (4.7)
|
24.7 (4.1)
|
0.002
|
24.0 (4.5)
|
0.001
|
3.6 (7.7 to 2.0)
|
0.002
|
|
Usual care
|
21.7 (4.4)
|
19.6 (10.4)
|
0.43
|
–
|
–
|
|
FACT-General
|
|
Exercise
|
77.2 (9.0)
|
88.3 (9.9)
|
< 0.001
|
88.1 (9.2)
|
< 0.001
|
11.1 (16.4 to 7.7)
|
< 0.001
|
|
Usual care
|
77.0 (9.1)
|
76.7 (9.0)
|
0.54
|
–
|
–
|
|
FACT-Breast
|
|
Exercise
|
98.3 (14.1)
|
113.0 (13.0)
|
< 0.001
|
112.1 (13.2)
|
< 0.001
|
14.7 (18.2 to 9.7)
|
< 0.001
|
|
Usual care
|
98.7 (14.4)
|
96.3 (14.5)
|
0.44
|
–
|
–
|
|
Trial outcome index
|
|
Exercise
|
60.2 (7.3)
|
69.9 (7.5)
|
< 0.001
|
69.0 (7.7)
|
< 0.001
|
8.8 (15.3 to 4.3)
|
< 0.001
|
|
Usual care
|
60.8 (7.5)
|
58.6 (7.4)
|
0.64
|
–
|
–
|
- Abbreviations: SD standard deviation, CI confidence interval, FACT Functional Assessment of Cancer Therapy
- aP value for repeated measures ANOVA comparing changes in the exercise group from baseline to post-intervention, and in the usual care group from baseline to post-intervention
- bP value for repeated measures ANOVA comparing changes in the exercise group from baseline to 3-month follow-up
- cP value for mixed model analysis comparing changes between the exercise and usual care group from baseline to post-intervention
