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Table 3 Comparison of breast cancer-specific quality of life between exercise and usual care groups

From: Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial

  Baseline Post-intervention 3-month follow-up Between-group difference post-intervention
Mean (SD) Mean (SD) P valuea Mean (SD) P valueb Mean (95% CI) P valuec
Physical well-being
 Exercise 19.2 (3.1) 23.2 (3.0) < 0.001 23.1 (3.2) < 0.001 3.9 (7.2 to 1.7) 0.003
 Usual care 19.1 (3.4) 19.1 (3.5) 0.74
Social well-being
 Exercise 19.7 (3.0) 23.0 (3.2) < 0.001 23.0 (3.0) < 0.001 3.3 (6.9 to 1.1) 0.005
 Usual care 19.6 (3.1) 19.5 (3.0) 0.81
Emotional well-being
 Exercise 18.4 (2.6) 20.1 (3.1) 0.01 20.1 (3.5) 0.01 1.7 (3.4 to 0.8) 0.01
 Usual care 18.3 (2.5) 18.2 (2.7) 0.75
Functional well-being
 Exercise 19.9 (3.4) 22.0 (3.2) 0.01 21.9 (3.1) 0.01 2.0 (4.2 to 0.6) 0.01
 Usual care 20.0 (3.6) 19.9 (3.3) 0.83
Additional concerns
 Exercise 21.1 (4.7) 24.7 (4.1) 0.002 24.0 (4.5) 0.001 3.6 (7.7 to 2.0) 0.002
 Usual care 21.7 (4.4) 19.6 (10.4) 0.43
FACT-General
 Exercise 77.2 (9.0) 88.3 (9.9) < 0.001 88.1 (9.2) < 0.001 11.1 (16.4 to 7.7) < 0.001
 Usual care 77.0 (9.1) 76.7 (9.0) 0.54
FACT-Breast
 Exercise 98.3 (14.1) 113.0 (13.0) < 0.001 112.1 (13.2) < 0.001 14.7 (18.2 to 9.7) < 0.001
 Usual care 98.7 (14.4) 96.3 (14.5) 0.44
Trial outcome index
 Exercise 60.2 (7.3) 69.9 (7.5) < 0.001 69.0 (7.7) < 0.001 8.8 (15.3 to 4.3) < 0.001
 Usual care 60.8 (7.5) 58.6 (7.4) 0.64
  1. Abbreviations: SD standard deviation, CI confidence interval, FACT Functional Assessment of Cancer Therapy
  2. aP value for repeated measures ANOVA comparing changes in the exercise group from baseline to post-intervention, and in the usual care group from baseline to post-intervention
  3. bP value for repeated measures ANOVA comparing changes in the exercise group from baseline to 3-month follow-up
  4. cP value for mixed model analysis comparing changes between the exercise and usual care group from baseline to post-intervention