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Fig. 4 | Breast Cancer Research

Fig. 4

From: Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models

Fig. 4

Analysis of breast cancer lung metastasis in humanized nonobese diabetic/severe combined immunodeficiency IL2Rγnull (hNSG) patient-derived xenograft (PDX). IHC analysis of human Ki-67, cytokeratin 19, and CD45+ expression in primary (breast) and metastatic (lung) triple-negative breast cancer PDX tumor lines BCM-2147, MC1, and BCM-4913 engrafted in hNSG mice. Amplifications, 4× and 20×; counterstain, hematoxylin

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