Fig. 5
From: Paternal malnutrition programs breast cancer risk and tumor metabolism in offspring
The AMPK signaling pathway is suppressed in low-protein (LP) diet mammary tissues and tumors. a Schematic representation of the interaction between miR-200c, miR-451a, and miR-92a1 with members of the AMP-activated protein kinase (AMPK) pathway. b,c Representative Western blots for CAB39, phospho-AMPK, AMPK, phospho-mTOR1, and mTOR1 on PND50 control (Con) and LP mammary tissues (b) (n = 4–7/group) and tumors (c) (n = 5/group). CAB39 protein levels were normalized by β-actin or β-tubulin. Phosphorylated proteins were normalized using the respective total protein levels