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Table 1 Characteristics of patients with early breast cancer

From: Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

  All patients No relapse Relapse  
Characteristic Number Percentage Number Percentage Number Percentage P
Number of patients 133   84 63 49 37  
Age (years)        nsa
 Median 54 52 56  
 Range 27–79 35–79 27–75  
Menopausal status        nsa
 Premenopausal 57 42,9 40 47.6 17 34.7  
 Postmenopausal 76 57.1 44 52.4 32 65.3  
Tumor size (cm)        0.015a
 T1 60 45.1 42 50 18 36.7  
 T2 66 49.6 41 48.8 25 51  
 T3 7 5,3 1 1.2 6 12.3  
Histological grade        nsa
 I 6 4.5 6 7.1    
 II 59 44.5 41 48.8 18 36.7  
 III 58 43.6 31 36.9 27 55.1  
 Lobular 5 3.7 3 3.6 2 4.1  
 Unknown 5 3.7 3 3.6 2 4.1  
Infiltrated lymph nodes        0.001a
 0 49 36.8 37 44.0 12 24.5  
 1–3 44 33.1 28 33.3 16 32.7  
  ≥ 4 34 25.6 13 15.5 21 42.8  
 Unknown 6 4.5 6 7.2    
ER status        
 Positive 88 66.2 56 66.7 32 65.3  
 Negative 43 32.3 26 31 17 34.7 nsa
 Unknown 2 1.5 2 2.3    
PR status        nsa
 Positive 90 67.7 61 72.6 29 59.2  
 Negative 41 30.8 21 25 20 40.8  
 Unknown 2 1.5 2 2.4    
HER2 status        nsa
 Positive 15 11.3 7 8.3 8 16.3  
 Negative 112 84.2 72 85.7 40 81.6  
 Unknown 6 4.5 5 6 1 2.1  
Adjuvant chemotherapy        nsa
 Anthracycline-based 13 9.8 9 10.7 4 8.2  
 Taxanes+anthracyclines 90 67.7 51 60.7 39 79.6  
 Taxane-based 21 15.8 15 17.9 6 12.2  
 Others 9 6.7 9 10.7    
Hormone therapy        nsa
 Yes 103 77.5 68 80.9 35 71.4  
 No 28 21.0 14 16.7 14 28.6  
 Unknown 2 1.5 2 2.4    
  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, ns not significant
  2. aPearson’s chi-squared test for comparison between patients with relapse and without relapse