Fig. 4

Normalized changes in amide proton transfer (APT) signal after the first cycle of neoadjuvant chemotherapy in the slice with the largest tumor diameter a and in the whole tumor b. The mean of the nonresponders (bright red line), partial responders (bright blue line), and complete responders (bright green line) on top of the change in APT signal of all the lesions (transparent lines in the background), where each line represents a different lesion. The standard deviation in each group is shown as error bars