Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study

Table 6 Comparison of longitudinal changes in neuropsychological scores in the chemotherapy subgroup and the healthy control (HC) group

	Non-TC (n = 9)	TC (n = 7)	HC (n = 14)	Non-TC vs. HC, p	Non-TC vs. TC, p	TC vs. HC, p
Crystallized composite	−0.17	−0.49	− 0.33	0.96	0.92	0.96
Fluid composite	−4.23	6.67	5.86	0.04	0.06	0.88
Total composite	− 2.94	1.58	3.63	0.12	0.35	0.64
Dimensional change card sort	−1.99	4.94	5.13	0.11	0.19	0.97
Flanker inhibitory control	−5.29	−0.69	2.82	0.07	0.38	0.46
Working memory	5.31	5.90	4.83	0.93	0.93	0.85
Oral reading recognition	−1.22	−6.94	0.09	0.62	0.07	0.02
Processing speed	−6.17	7.59	−1.45	0.45	0.07	0.18
Episodic memory	−4.85	1.62	6.80	0.12	0.46	0.52
Picture vocabulary	−0.05	7.46	−1.48	0.68	0.08	0.02
Picture vocabulary	−0.05	7.46	−1.48	0.68	0.08	0.02

The TC subgroup (n = 7) included the patients on the docetaxel and cyclophosphamide chemotherapy regimen. The non-TC subgroup (n = 9) included the patients on a chemotherapy regimen other than the TC regimen. Bold numbers indicate key findings

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