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Table 2 Multivariable analysis of patient demographics and characteristics comparing patients who did not receive chemotherapy to patients who did receive chemotherapy

From: Practice patterns and outcomes for patients with node-negative hormone receptor-positive breast cancer and intermediate 21-gene Recurrence Scores

 

Adjusted odds ratio

95% confidence interval

p value

Facility type

 Community cancer program

1.26

1.07–1.49

0.01

 Comprehensive community cancer program

1.20

1.09–1.32

< 0.001

 Academic/research program

REF

  

 Other

1.13

0.95–1.33

0.16

Age category (years)

 < 40

REF

  

 40–49

0.48

0.38–0.61

< 0.001

 50–59

0.34

0.27–0.43

< 0.001

 60–69

0.20

0.16–0.26

< 0.001

 70–79

0.10

0.07–0.14

< 0.001

 80+

0.07

0.03–0.16

< 0.001

Race/ethnicity

 Non-Hispanic White

REF

  

 Non-Hispanic Black

1.10

0.94–1.40

0.26

 Hispanic

1.04

0.85–1.27

0.73

 Non-Hispanic Asian/Pacific

0.94

0.76–1.17

0.60

 Other

1.15

0.94–1.40

0.19

Primary payer

 Not insured

1.09

0.80–1.48

0.59

 Private insurance

REF

  

 Medicaid

0.91

0.76–1.09

0.30

 Medicare

0.73

0.63–0.85

< 0.001

 Other

0.79

0.58–1.08

0.14

Urban/rural

 Metro counties

REF

  

 Urban counties

0.87

0.76–1.00

0.05

 Rural counties

1.30

0.95–1.79

0.10

 Unknown

0.84

0.63–1.12

0.22

Charlson–Deyo score

 0

REF

  

 1

1.09

0.95–1.24

0.22

 2

0.73

0.49–1.08

0.11

Grade

 Well differentiated, differentiated, NOS

REF

  

 Moderately differentiated, moderately well differentiated, intermediate differentiation

1.72

1.54–1.91

< 0.001

 Poorly differentiated

3.76

3.28–4.31

< 0.001

AJCC pathologic stage

 T1C

REF

  

 T2

1.62

1.48–1.77

< 0.001

Lymphovascular invasion

 Not present

REF

  

 Present

1.41

1.25–1.59

< 0.001

Type of surgery

 Breast conservation

REF

  

 Mastectomy

1.35

1.06–1.72

0.02

Margin status

 Negative

REF

  

 Positive

1.15

0.92–1.44

0.23

 Unknown

1.05

0.45–2.46

0.90

Radiation therapy

 None

REF

  

 Beam radiation

0.35

0.01–8.40

0.51

Radiation treatment volume

 No radiation treatment

0.25

0.01–6.20

0.40

 Breast or chest wall

REF

  

 Breast/lymph nodes or chest wall/lymph nodes

1.24

0.96–1.61

0.10

 Other

2.36

1.05–5.30

0.04

 Unknown

1.30

0.56–3.04

0.54

  1. AJCC American Joint Committee on Cancer, NOS not otherwise specified, REF reference