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Table 2 Associations between leukocyte telomere length and breast cancer risk

From: Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Stratum Relative LTLa Controls Cases OR 95% CI p value
Overall Quartile 1 (0.36–0.63) 134 81 Reference
  Quartile 2 (0.63–0.75) 126 102 1.60 (1.04–2.46) 3.17E-02
  Quartile 3 (0.75–0.93) 134 172 2.28 (1.46–3.57) 2.89E-04
  Quartile 4 (0.93–1.94) 139 215 2.71 (1.58–4.65) 3.07E-04
  Continuous variable 533 570 3.20 (1.57–6.55) 1.41E-03
ER+ Quartile 1 (0.36–0.63) 134 41 Reference
  Quartile 2 (0.63–0.75) 126 45 1.59 (0.88–2.89) 1.25E-01
  Quartile 3 (0.75–0.93) 134 77 2.97 (1.54–5.72) 1.11E-03
  Quartile 4 (0.93–1.94) 139 86 2.55 (1.10–5.86) 2.82E-02
  continuous variable 533 249 3.33 (1.17–9.46) 2.38E-02
ER− Quartile 1 (0.36–0.63) 134 28 Reference
  Quartile 2 (0.63–0.75) 126 40 1.25 (0.65–2.44) 5.05E-01
  Quartile 3 (0.75–0.93) 134 79 1.67 (0.88–3.16) 1.19E-01
  Quartile 4 (0.93–1.94) 139 104 2.12 (1.04–4.31) 3.84E-02
  Continuous variable 533 251 2.33 (0.88–6.15) 8.92E-02
  1. ER Estrogen receptor, LTL Leukocyte telomere length
  2. aAnalyses are adjusted for age, body mass index, smoking, center of origin, and plate
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