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Table 5 Mean percentages of pathological response per MRI-based response pattern (mean percentage of reader 1 and 2) halfway through and after NAC

From: MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer

  MRI halfway through NAC MRI after NAC
Percentage of total (N = 75) Tumor response > 50% Diameter reduction > 50% pCR Percentage of total (N = 57) Tumor response > 50% Diameter reduction > 50% pCR
Complete radiologic response (type 0) 8% 90% 83% 83% 20% 96% 61% 41%
Concentric shrinkage (type 1) 40% 78% 37% 26% 24% 61% 44% 18%
Crumbling (type 2) 30% 65% 40% 14% 23% 69% 43% 8%
Diffuse enhancement (type 3) 2% n.a. n.a. n.a. 9% n.a. n.a. n.a.
Stable disease (type 4) 21% 53% 39% 3% 24% 38% 11% 4%
Progressive disease (type 5) 1% n.a. n.a. n.a. 2% 50% 0% 0%
Total 100% 69% 41% 21% 100% 65% 38% 16%
  1. Abbreviations: MRI magnetic resonance imaging, NAC neoadjuvant chemotherapy and immunotherapy, pCR pathological complete response, n.a. not applicable
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