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Table 4 MRI-based response patterns of breast carcinomas on breast MRI after NAC and pathological response per MRI-based response pattern

From: MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer

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Number (percentage) Tumor response > 50% Diameter reduction > 50% pCR Number (percentage) Tumor response > 50% Diameter reduction > 50% pCR
Complete radiologic response (type 0) 13 (23%) 12/13 (92%) 7/12a (58%) 5/13 (38%) 9 (16%) 9/9 (100%) 5/8a (63%) 4/9 (44%)
Concentric shrinkage (type 1) 19 (33%) 11/19 (58%) 7/19 (37%) 2/19 (11%) 8 (14%) 5/8 (63%) 4/8 (50%) 2/8 (25%)
Crumbling (type 2) 11 (19%) 7/11 (64%) 5/11 (45%) 1/11 (9%) 15 (26%) 11/15 (73%) 6/15 (40%) 1/15 (6%)
Diffuse enhancement (type 3) 0 (0%) n.a. n.a. n.a. 10 (18%) 8/10 (80%) 5/10 (50%) 2/10 (20%)
Stable disease (type 4) 13 (23%) 6/13 (46%) 2/13 (15%) 1/13 (8%) 14 (25%) 4/14 (29%) 1/14 (7%) 0/14 (0%)
Progressive disease (type 5) 1 (2%) 1/1 (100%) 0/1 (0%) 0/1 (0%) 1 (2%) 0/1 (0%) 0/1 (0%) 0/1 (0%)
Total 57 (100%) 37/57 (65%) 21/56a (38%) 9/57 (16%) 57 (100%) 37/57 (65%) 21/56a (38%) 9/57 (16%)
  1. Abbreviations: MRI magnetic resonance imaging, NAC neoadjuvant chemotherapy and immunotherapy, pCR pathological complete response
  2. aIn one tumor no diameter assessment was possible on baseline MRI
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