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Table 4 MRI-based response patterns of breast carcinomas on breast MRI after NAC and pathological response per MRI-based response pattern

From: MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer

 

Reader 1

Reader 2

Number (percentage)

Tumor response > 50%

Diameter reduction > 50%

pCR

Number (percentage)

Tumor response > 50%

Diameter reduction > 50%

pCR

Complete radiologic response (type 0)

13 (23%)

12/13 (92%)

7/12a (58%)

5/13 (38%)

9 (16%)

9/9 (100%)

5/8a (63%)

4/9 (44%)

Concentric shrinkage (type 1)

19 (33%)

11/19 (58%)

7/19 (37%)

2/19 (11%)

8 (14%)

5/8 (63%)

4/8 (50%)

2/8 (25%)

Crumbling (type 2)

11 (19%)

7/11 (64%)

5/11 (45%)

1/11 (9%)

15 (26%)

11/15 (73%)

6/15 (40%)

1/15 (6%)

Diffuse enhancement (type 3)

0 (0%)

n.a.

n.a.

n.a.

10 (18%)

8/10 (80%)

5/10 (50%)

2/10 (20%)

Stable disease (type 4)

13 (23%)

6/13 (46%)

2/13 (15%)

1/13 (8%)

14 (25%)

4/14 (29%)

1/14 (7%)

0/14 (0%)

Progressive disease (type 5)

1 (2%)

1/1 (100%)

0/1 (0%)

0/1 (0%)

1 (2%)

0/1 (0%)

0/1 (0%)

0/1 (0%)

Total

57 (100%)

37/57 (65%)

21/56a (38%)

9/57 (16%)

57 (100%)

37/57 (65%)

21/56a (38%)

9/57 (16%)

  1. Abbreviations: MRI magnetic resonance imaging, NAC neoadjuvant chemotherapy and immunotherapy, pCR pathological complete response
  2. aIn one tumor no diameter assessment was possible on baseline MRI