Fig. 3

Associations between proteins and area-based mammographic breast density. The 11 candidate proteins expressed in breast tissue (see Tables 2 and 3) and their relationships with absolute area-based mammographic density (AD) are shown. Data from the analysis of both sample sets are shown. The red lines represent the linear relationship between the measured protein levels after adjusting for body mass index, absolute volumetric breast density (VD) and the interaction between AD and VD, stated as “norm. MFI”. The x-axis depicts the log-scaled distribution of AD values. The density of data points is shown on a coloured heatmap, where data points are binned into rectangles. Darker and lighter blue colours indicate lower and higher density of data points, respectively