Skip to main content

Table 3 Gene transcripts differentially expressed in the bone marrow of WHIM17 lineage mice relative to both control mice and primary xenograft tumor

From: Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

Gene symbol

Gene name

Fold expression

p value

Targetable

CD53

CD53 molecule

4.1

0.0006062

 

PTPRC

Protein tyrosine phosphatase, receptor type C

3.7

0.00474656

 

KIR3DL1

Killer cell immunoglobulin like receptor, three Ig domains and long Cytoplasmic Tail 1

3.2

0.00145097

 

HBA1

Hemoglobin subunit alpha 1

2.7

0.00117262

 

MT3

Metallothionein 3

2.7

0.00033581

 

HBB

Hemoglobin subunit beta

2.7

0.00086439

 

OSM

Oncostatin M

2.5

0.00677886

 

MAP2K6

Mitogen-activated protein kinase kinase 6

2.5

0.00632423

 

ARHGDIB

Rho GDP dissociation inhibitor beta

2.4

0.00115363

 

SLPI

Secretory leukocyte peptidase inhibitor

2.3

0.00071176

 

DDC

Dopa Decarboxylase

2.3

0.00080507

Yes [40]

SSTR4

Somatostatin receptor 4

2.3

0.00058499

Yes [41, 42]

MAPT

Microtubule associated protein tau

2.3

0.0010915

 

HPR

Haptoglobin-related protein

2.3

0.00139515

 

SPN

Sialophorin

2.3

0.00092894

 

HLA-B

Major histocompatibility complex, class I, B

2.2

4.27E-05

 

CISH

Cytokine inducible SH2 containing protein

2.2

0.00021425

 

MST4

Serine/threonine protein kinase 26

2.1

0.0035196

 

SERPINA5

Serpin family A member 5

2.1

0.00622652

 

PTPN6

Protein tyrosine phosphatase, non-receptor type 6

2.1

0.00735724

 

MMP17

Matrix metallopeptidase 17

2.1

0.00493339

 

CEACAM6

Carcinoembryonic antigen related cell adhesion molecule 6

2.0

0.00179388

 
Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us