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Fig. 2 | Breast Cancer Research

Fig. 2

From: Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

Fig. 2

Z4OHtam and Z-endoxifen concentrations compared by CYP2D6 phenotype groups. Impaired CYP2D6 function correlates with lower levels of Z-4OHtam and Z-endoxifen (p = 0.05 and p <0.001, respectively; Kruskal-Wallis). Cut-off values representing patients with high levels (green line) and low levels (red line) of active metabolites are shown. EM extensive metabolizer, IM intermediate metabolizer, PM poor metabolizer, UM ultra-rapid metabolizer

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Breast Cancer Research

ISSN: 1465-542X

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