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Fig. 8 | Breast Cancer Research

Fig. 8

From: Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells

Fig. 8

Bone tissues express aromatase. Immunostaining with anti-aromatase H4 monoclonal antibody detects aromatase expression in the bone marrow compartment of trabecular bone tissue fragments. a Positive control placental tissue stained with (+) vs. without (−) primary antibody. b Paraffin-embedded breast cancer cell lines ER+ MCF-7, T-47D, ZR-75, and ER- SK-BR-3, MDA-MD-231, and MCF-10A stained with primary antibody. c Trabecular bone tissues from total hip replacement (THR) specimen 177 stained with (+) vs. without (−) primary antibody. d Additional bone tissues from THRs 177, 178 and 179 stained with primary antibody

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Breast Cancer Research

ISSN: 1465-542X

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