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Table 4 Univariate modelling results using the validation dataset

From: A novel and fully automated mammographic texture analysis for risk prediction: results from two case-control studies

Parameter

Standardized odds ratio

95% CI for odds ratio

χ2

P value

mC

95% CI for mC

Risk score

1.36

(1.20–1.55)

22.39

2.22E-06

0.58

(0.54– 0.62)

Coarseness

1.06

(0.92–1.22)

0.61

4.34E-01

0.50

(0.46– 0.54)

Contrast

0.87

(0.76–0.99)

4.33

3.75E-02

0.46

(0.42– 0.50)

SD

1.01

(0.89–1.15)

0.03

8.55E-01

0.50

(0.45– 0.54)

Sum average 16

1.29

(1.14–1.47)

15.37

8.85E-05

0.58

(0.54– 0.62)

Sum average 32

1.32

(1.1–1.50)

17.55

2.80E-05

0.58

(0.53– 0.62)

Sum average 64

1.38

(1.21–1.57)

23.81

1.06E-06

0.59

(0.55–0.63)

Volumetric PD

1.27

(1.11–1.46)

11.84

5.80E-04

0.57

(0.53– 0.61)

  1. Total number of observations (N) = 1248, including 317 cases and 931 controls. Standardized odds ratio is the change in odds for a standard deviation (in controls) increase in predictors, adjusted for age and body mass index. Sum average 16, 32 and 64 are the texture feature sum average using images downsized by a factor of 16, 32 and 64.
  2. PD percent density, CI confidence interval, mC matched concordance index, SD standard deviation
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Breast Cancer Research

ISSN: 1465-542X

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