Fig. 5
From: SPEN, a new player in primary cilia formation and cell migration in breast cancer
SPEN expression is predictive of distant metastasis-free survival in patients with ERα-negative breast cancer. a and b Kaplan-Meier graphs showing time to metastasis (a) and distant metastasis-free survival (b) in 77 and 170 patients with ERα-negative breast cancer. In both cases, the median was used as a cutoff. c and d Kaplan-Meier graphs showing time to metastasis (c) and distant metastasis-free survival (d) in 209 and 577 patients with ERα-positive breast cancer with high and low SPEN-expressing tumors. In both cases, the median was used as a cutoff. e and f Kaplan-Meier graphs showing distant metastasis-free survival in 170 ERα-negative (e) and 577 ERα-positive (f) patients with breast cancer with high and low KIF3A-expressing tumors. ERα Estrogen receptor alpha, SPEN Split ends