Skip to main content

Table 7 Multivariate association between biomarkers and RDI < 85%

From: Association of pre-chemotherapy peripheral blood pro-inflammatory and coagulation factors with reduced relative dose intensity in women with breast cancer

Biomarkers/Clinical factors Odds ratio (95%CI) P value
IL-6 or D-dimer combinationa
 1 or 2 vs. 0 2.54 (1.03–6.23) 0.04
Age 1.06 (1.02–1.10) <0.01
Physical function measured by MOS-ADLb 0.98 (0.96–1.00) 0.04
Breast cancer stage
 Stage II vs. I 0.66 (0.22–1.98) 0.46
 Stage III vs. I 0.23 (0.05–0.97) 0.04
Anthracycline-containing regimen
  1. a IL-6 or D-dimer combination: 0 = both markers in lower three quartiles; 1 = 1or 2 of the markers in the 4th quartile
  2. bMOS-ADL: Activities of Daily Living (subscale of MOS physical health)