Fig. 6From: Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashionIn-vivo study of drug response using cells carrying ZNF423 WT (CRISPR-ZR75-1) or variant genotypes. a Tumors removed from the mice in each treatment group (eight mice) after 30Ā days of drug treatment. b Tumor volume measured every 3Ā days during treatment. Volume shown as meanāĀ±āSEM for eight mice, comparisons between WT and variant performed with two-tailed Studentās t test. *pā<ā0.05, **pā<ā0.01, ***pā<ā0.001, ****pā<ā0.0001. Ola olaparib, PBS phosphate-buffered saline, Tam tamoxifen, WT wild typeBack to article page