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Table 1 Baseline characteristics of the stratified neoadjuvant and adjuvant radiotherapy cohorts

From: Neoadjuvant radiotherapy of early-stage breast cancer and long-term disease-free survival

  Number of patients (%) P value
Neoadjuvant RT (n = 2554) Adjuvant RT (n = 247,641)
Age, years 58.6 ± 12.9   59.5 ± 12.2   <0.0001a
Year of diagnosis 1995.7 ± 7.2   2003.1 ± 6.5   <0.0001a
Race
 White 2348 (91.9%) 206,775 (83.5%) <0.0001b
 Black 127 (5%) 21,169 (8.5%) <0.0001b
 Other 79 (3.1%) 19,697 (8%) <0.0001b
ER status
 Positive 1368 (53.6%) 168,797 (68.2%) <0.0001b
 Negative 353 (13.8%) 34,494 (13.9%) 0.88b
 Unknown 833 (32.6%) 44,350 (17.9%) <0.0001b
PR status
 Positive 1209 (47.3%) 144,228 (58.2%) <0.0001b
 Negative 492 (19.3%) 54,473 (22%) 0.0009b
 Unknown 853 (33.4%) 48,940 (19.8%) <0.0001b
Stage
 Carcinoma in situ 344 (13.5%) 52,691 (21.3%) <0.0001b
 T1 1390 (54.4%) 146,954 (59.3%) <0.0001b
 T2 294 (11.5%) 30,683 (12.4%) 0.1798b
 T3 49 (1.9%) 3034 (1.2%) 0.0016b
 Unknown 477 (18.7%) 14,279 (5.8%) <0.0001b
Histology
 Ductal 2215 (86.7%) 213,143 (86.1%) 0.3397b
 Lobular 146 (5.7%) 14,270 (5.8%) 0.9212b
 Other 193 (7.6%) 20,228 (8.2%) 0.2614b
Type of surgery
 Partial mastectomy 2192 (85.8%) 233,946 (94.5%) <0.0001b
 Mastectomy 269 (10.5%) 10,632 (4.3%) <0.0001b
 Other 93 (3.6%) 3063 (1.2%) <0.0001b
  1. ER Estrogen receptor, PR progesterone receptor
  2. Age and year of diagnosis are reported as mean ± SD
  3. a Wilcoxon rank-sum test with normal approximation
  4. b Pearson’s chi-square test