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Table 4 Top ten radiomic features identified in each experiment

From: Intratumoral and peritumoral radiomics for the pretreatment prediction of pathological complete response to neoadjuvant chemotherapy based on breast DCE-MRI

Rank

Feature family

Descriptor

Location

Phase

Statistic

Experiment 1

 All-comers

  1

CoLlAGe

Information measure of correlation 1

Intratumoral

Initial

Kurtosis

  2

Laws

Spot-ripple

Intratumoral

Initial

Skewness

  3

Laws

Level-spot

Peritumoral

Peak

SD

  4

CoLlAGe

Entropy

Peritumoral

Initial

Kurtosis

  5

CoLlAGe

Sum average

Intratumoral

Peak

SD

  6

Laws

Edge-wave

Peritumoral

Initial

Mean

  7

CoLlAGe

Energy

Intratumoral

Initial

Median

  8

Laws

Wave-spot

Intratumoral

Initial

Skewness

  9

CoLlAGe

Inverse difference moment

Peritumoral

Peak

Kurtosis

  10

CoLlAGe

Correlation

Intratumoral

Peak

Kurtosis

Experiment 2

 HR+, HER2−

  1

CoLlAGe

Entropy

Peritumoral

Initial

Kurtosis

  2

CoLlAGe

Difference entropy

Peritumoral

Initial

Skewness

  3

CoLlAGe

Sum entropy

Peritumoral

Initial

Skewness

  4

Laws

Level-ripple

Intratumoral

Peak

Kurtosis

  5

CoLlAGe

Inertia

Intratumoral

Peak

Skewness

  6

Gabor

f = 0, θ = 22.5 degrees

Intratumoral

Initial

Median

  7

Laws

Edge-edge

Peritumoral

Initial

Skewness

  8

Gabor

f = 2, θ = 22.5 degrees

Intratumoral

Initial

Kurtosis

  9

CoLlAGe

Inverse difference moment

Peritumoral

Peak

Skewness

  10

Haralick

Correlation

Peritumoral

Peak

SD

 TN/HER2+

  1

Laws

Level-ripple

Peritumoral

Peak

Mean

  2

CoLlAGe

Information measure of correlation 1

Intratumoral

Initial

Skewness

  3

CoLlAGe

Information measure of correlation 2

Peritumoral

Peak

Mean

  4

CoLlAGe

Energy

Intratumoral

Initial

Median

  5

Laws

Spot-level

Peritumoral

Initial

Median

  6

Gabor

f = 2, θ = 135 degrees

Intratumoral

Peak

Kurtosis

  7

Laws

Level-wave

Peritumoral

Initial

Median

  8

Laws

Edge-spot

Peritumoral

Peak

Skewness

  9

CoLlAGe

Difference variance

Peritumoral

Peak

Kurtosis

  10

Gabor

f = 2, θ = 22.5 degrees

Intratumoral

Initial

Skewness

  1. Abbreviations: CoLlAGe Co-occurrence of Local Anisotropic Gradient Orientations, HER2 Human epidermal growth factor receptor 2, HR Hormone receptor, TN Triple-negative