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Table 2 Baseline characteristics of the study population (n = 19)

From: A phase-I study of lapatinib in combination with foretinib, a c-MET, AXL and vascular endothelial growth factor receptor inhibitor, in human epidermal growth factor receptor 2 (HER-2)-positive metastatic breast cancer

Characteristic

Value

Age, years, median (range)

60 (34–86)

Performance status, n

 0

9

 1

9

 2

1

Measurable disease, n (%)

16 (84)

Prior therapy, n

 Chemotherapy

17

 Hormonal therapy

7

 HER-2 inhibitor

18

 Radiotherapy

15

ER-positive, n (%)

10 (53%)

HER-2 positive, n (%)

19 (100%)

Number of sites of disease, n (%)

 1

5 (26%)

 2

2 (11%)

 3

6 (32%)

 ≥4

6 (32%)

Site of disease, n (%)

 Bone

9 (47%)

 Soft tissue

10 (53%)

 Brain

2 (11%)

 Lung/liver

16 (84%)

  1. n number of patients, HER-2 human epidermal growth factor receptor 2, ER estrogen receptor