Table 1 Histological and immunohistochemical staining of the primary breast cancer tissue from patients with leptomeningeal metastasis
Case number | Histology | pTNM | ER | PgR | HER2 |
|---|---|---|---|---|---|
1 | na | na | na | na | na |
2 | Infiltrating ductal carcinoma | na | pos | pos | neg |
3 | Infiltrating ductal carcinoma | pTc1, N0, stage 1 | neg | neg | neg |
4 | Infiltrating lobular carcinoma | na | neg | pos | pos |
5 | na | na | na | na | na |
6 | Infiltrating ductal carcinoma | pT4b, N3a, M1 (UICC 2002) | 40% | 70% | neg |
7 | Infiltrating lobular carcinoma | pT2, pN3a, M0 | 75% | 100% | pos |
8 | na | na | na | na | na |
9 | Infiltrating lobular carcinoma | pT1c, N1bi, Mx (UICC 1997) | 30% | 30% | neg |
10 | Infiltrating ductal carcinoma | na | pos | pos | neg |
11 | Infiltrating lobular multifocal | pT1c (m); pN1biv; Mx (UICC 1997) | 20% | 20% | pos |
12 | Infiltrating ductal carcinoma | na | neg | neg | neg |
13 | Infiltrating ductal carcinoma | pT1c(m), N2, Mx (UICC 2002) | neg | 40% | pos |