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Fig. 5 | Breast Cancer Research

Fig. 5

From: Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer

Fig. 5

Thymosin beta 10 (TMSB10) promotes proliferation and metastasis via activating the AKT/FOXO signaling pathway in breast cancer. a Western blotting analysis of AKT/FOXO-associated proteins in the indicated breast cancer cells. b and c Relative AKT activity and FOXO reporter activity in the indicated cells. Each bar represents the mean values ± SD of three independent experiments. *P < 0.05. d-g Colony formation, anchorage-independent growth, migration and invasion assay revealed the effect of perifosine on the indicated cells. Each bar represents the mean values ± SD of three independent experiments. *P < 0.05. DMSO dimethyl sulfoxide

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