Fig. 1From: Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trialDerivation of the Tamoxifen and Exemestane Trial (TEXT) translational cohort from the intention-to-treat (ITT) population. The translational cohort includes patients whose blood was available for DNA analysis. GNRHa triptorelin was required for the first 6Â months, any time after which the patient could choose to undergo bilateral oophorectomy or bilateral ovarian radiotherapy. E exemestane, T tamoxifen, OFS ovarian function suppression, LFU lost to follow up, CRF case report formBack to article page