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Fig. 3 | Breast Cancer Research

Fig. 3

From: PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells

Fig. 3

Protein tyrosine kinase C theta isoform (PRKCQ) kinase activity is required for epidermal growth factor (EGF)-independent growth, Extracellular signal-related kinase (Erk activity) and retinoblastoma (Rb) phosphorylation. a MCF-10A cells expressing vector control, constitutively active (A148E) or kinase-inactive (K409R) PKCθ, were cultured in growth media lacking EGF. Cell lysates were probed with the indicated antibodies. b MCF-10A cells expressing vector control, active or kinase-dead PKCθ, were cultured in media lacking EGF for the indicated number of days and counted

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Breast Cancer Research

ISSN: 1465-542X

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