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Fig. 5 | Breast Cancer Research

Fig. 5

From: Proteomic analysis of breast tumors confirms the mRNA intrinsic molecular subtypes using different classifiers: a large-scale analysis of fresh frozen tissue samples

Fig. 5

Cluster analysis of all tumors analyzed with the selected reaction monitoring protein assay. The tumor classification according to three gene expression profiling methods is indicated below the branching and colored accordingly: the tumor classification according to three gene expression profiling methods is indicated below the branching and colored accordingly: red basal-like, magenta human epidermal growth factor receptor 2, green normal-like, blue luminal A, turquoise luminal B, gray unknown classification. Clinical parameters including BRCA1 methylation status (pink positive), BRCA mutational status (pink BRCA1-positive, yellow BRCAx-positive), estrogen receptor (ER) (dark blue positive), and progesterone receptor (PgR) (darker purple positive) status and overall survival (green alive) are indicated below the samples. Proteins are indicated with the SwissProt ID and short name. PAM50 prediction analysis of microarray

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