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Table 2 Association between germline APOBEC3B deletion and breast cancer risk in Malaysian women

From: Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation

Genotype

Cases

(N = 1451)

n (%)

Controls

(N = 1442)

n (%)

OR (95 % Cl)a

A3B wt/wt

591 (40.7)

670 (46.5)

1.00 (reference)

A3B del/wt

649 (44.7)

599 (41.5)

1.23 [1.05, 1.44]

A3B del/del

211 (14.5)

173 (12.0)

1.38 [1.10, 1.74]

P trend b

  

0.005

  1. A3B wt/wt no deletion, A3B del/wt one-copy deletion, A3B del/del two-copy deletion
  2. aAdjusted for age
  3. bTest for trends of odds were two-sided and based on likelihood ratio tests
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Breast Cancer Research

ISSN: 1465-542X

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