Table 3 p value of log-rank test and HRs of Cox regression on RFS comparing breast cancer patients with different HGs and predicted groups in HG2 tumours
From: Determining breast cancer histological grade from RNA-sequencing data
N | Events | Log-rank test | HR unadjusted a | HR adjusted b | |
|---|---|---|---|---|---|
(p value) | (95 % CI) | (95 % CI) | |||
Histologic grades | |||||
HG1 | 98 | 6 | 0.017 ∗ | 1.00 (Reference) | 1.00 (Reference) |
HG3 | 294 | 44 | 2.62 (1.04–6.61) ∗ | 2.02 (0.76–5.40) | |
GGI | |||||
Low risk | 223 | 12 | 0.010 ∗ | 1.00 (Reference) | 1.00 (Reference) |
High risk | 110 | 15 | 2.64 (1.23–5.70) ∗ | 3.04 (1.35–6.81) ∗ | |
TG-Gene | |||||
Low risk | 228 | 13 | 0.018 ∗ | 1.00 (Reference) | 1.00 (Reference) |
High risk | 105 | 14 | 2.43 (1.13–5.20) ∗ | 2.50 (1.14–5.50) ∗ | |
TG-Iso | |||||
Low risk | 216 | 11 | 0.014 ∗ | 1.00 (Reference) | 1.00 (Reference) |
High risk | 117 | 16 | 2.53 (1.17–5.47) ∗ | 2.64 (1.20–5.79) ∗ | |
SC-Gene | |||||
Low risk | 198 | 14 | 0.584 | 1.00 (Reference) | 1.00 (Reference) |
High risk | 117 | 11 | 1.25 (0.56–2.78) | 1.23 (0.54–2.77) | |
SC-Iso | |||||
Low risk | 208 | 14 | 0.393 | 1.00 (Reference) | 1.00 (Reference) |
High risk | 107 | 11 | 1.41 (0.64–3.14) | 1.45 (0.65–3.24) |