Table 1 Clinical characteristics of subjects in the Clinseq and TCGA data sets
From: Determining breast cancer histological grade from RNA-sequencing data
| Â | Clinseq | TCGA |
|---|---|---|
N | 275 | 487 |
Median age (range) | 61 (28–94) | 57 (26–90) |
Histologic grade | Â | Â |
Grade 1 (%) | 39 (14.2 %) | 64 (13.1 %) |
Grade 2 (%) | 121 (44.0 %) | 228 (46.8 %) |
Grade 3 (%) | 115 (41.8 %) | 195 (40.0 %) |
Tumour size | Â | Â |
≥20 mm (%) | 150 (54.6 %) | 317 (65.1 %) |
<20 mm (%) | 125 (45.5 %) | 170 (34.9 %) |
Lymph node status | Â | Â |
Positive (%) | 39 (14.2 %) | 260 (53.4 %) |
Negative (%) | 136 (85.8 %) | 227 (46.6 %) |
ER status | Â | Â |
Positive (%) | 231 (84.0 %) | 384 (78.9 %) |
Negative (%) | 42 (15.3 %) | 102 (20.9 %) |
NA (%) | 2 (0.7 %) | 1 (0.2 %) |
PR status | Â | Â |
Positive (%) | 175 (63.6 %) | 334 (68.6 %) |
Negative (%) | 98 (35.6 %) | 151 (31.0 %) |
NA (%) | 2 (0.7 %) | 2 (0.4 %) |
HER2 status | Â | Â |
Positive (%) | 44 (16.0 %) | 60 (12.3 %) |
Negative (%) | 225(81.8 %) | 274 (56.3 %) |
Equivocal (%) | – | 108 (22.2 %) |
NA (%) | 6 (2.2 %) | 45 (9.2 %) |
KI67 status a | Â | Â |
Positive (%) | 131 (47.6 %) | – |
Negative (%) | 121 (44.0 %) | – |
NA (%) | 23 (8.4 %) | – |