Table 3 Stability of the mutant allele

M01 c.1A > G

3

0.7 (0.6–0.8)

49 (42–55)

52 (51–52)

49 (49–49)

No

M02 c.1A > C

2

/

/

/

/

No

M03 c.212 + 3A > G

2

/

/

/

/

No

M04 c.1961del

0

0.4 (0.4–0.4)

29 (25–33)

47 (43–51)

47 (47–47)

Yes

M05 c.2359dup

3

0.6 (0.6–0.6)

28 (25–31)

42 (38–45)

48 (48–48)

Yes

M06 c.2359dup

2

0.5 (0.5–0.5)

24 (23–25)

44 (41–47)

50 (50–50)

Yes

M07 c.2359dup

0

0.4 (0.4–0.5)

29 (27–30)

48 (30–67)

57 (55–59)

Yes

M08 c.2359dup

4

/

/

/

/

Yes

M09 c.3331_3334del

1

0.4 (0.4–0.4)

25 (18–31)

44 (34–48)

49 (49–49)

Yes

M10 c.3481_3491del

2

0.4 (0.4–0.4)

23 (16–30)

42 (28–52)

39 (32–46)^a

Yes

M11 c.3481_3491del

1

0.4 (0.3–0.5)

23 (16–32)

41 (23–54)

39 (34–44)^a

Yes

M12 c.3481_3491del

2

0.4 (0.4–0.4)

26 (16–34)

39 (28–50)

42 (35–49)^a

Yes

M13 c.3661G > T

1

0.5 (0.3–0.6)

29 (28–30)

50 (41–57)

50 (46–53)

Yes

M14 c.3661G > T

0

0.4 (0.3–0.4)

31 (29–32)

52 (52–52)

50 (50–50)

Yes

M15 c.3661G > T

0

/

/

/

/

Yes

M16 c.4327C > T

3

0.5 (0.5–0.6)

24 (21–27)

51 (45–56)

/

Yes

M17 c.4327C > T

3

0.6 (0.4–0.7)

26 (21–30)

48 (44–53)

50 (50–50)

Yes

M18 c.4931_4393delinsTT

0

0.4 (0.3–0.4)

30 (28–31)

37 (28–47)

52 (52–52)

Yes