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Table 1 Demographic and clinicopathological features of the 47 analyzed metastatic breast cancer patients

From: In patients with metastatic breast cancer the identification of circulating tumor cells in epithelial-to-mesenchymal transition is associated with a poor prognosis

Age

 Median (range)

62 (36–82)

 < 70 years

36 (77 %)

 ≥ 70 years

11 (23 %)

ECOG PS, n (%)

 

 0

29 (62 %)

 1

14 (29 %)

 2

4 (9 %)

Immunophenotype, n (%)

 Luminal-like

25 (54 %)

 HER2-positive

11 (23 %)

 Triple negative

11 (23 %)

Histotype, n (%)

 Ductal

38 (84 %)

 Lobular

7 (16 %)

Metastatic sites,a n (%)

 Bone

29 (62 %)

 Liver

22 (47 %)

 Lung

16 (34 %)

 CNS

3 (6 %)

Number of metastatic sites, n (%)

 1

16 (34 %)

 ≥ 2

31 (66 %)

Number of previous lines, n (%)

 0

15 (32 %)

 1

9 (19 %)

 ≥ 2

23 (49 %)

Type of treatments received, n (%)

 Chemotherapy

33 (70 %)

 Endocrine therapy

6 (13 %)

 Chemotherapy and endocrine therapy

5 (11 %)

 Palliative care

2 (6 %)

 Anti-HER2 targeted therapy

12 (26 %)

  1. aPatients may have more than one site involved
  2. ECOG PS Eastern Cooperative Oncology Group Performance Status, CNS central nervous system, HER2 human epidermal growth factor receptor 2