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Fig. 3 | Breast Cancer Research

Fig. 3

From: In patients with metastatic breast cancer the identification of circulating tumor cells in epithelial-to-mesenchymal transition is associated with a poor prognosis

Fig. 3

Association between CTC subpopulations and clinicopathological characteristics. Box and whiskers plots showing median, interquartile ranges, 5th and 95th percentile of the absolute number or frequency of different classes of cells (E, E/M, MES, NEG) significantly associated with specific clinicopathological features. E CTC cells expressing only epithelial markers, EM CTC cells coexpressing mesenchymal and epithelial markers, ETOT CTC CD45neg cells expressing epithelial markers, independently from the expression of mesenchymal markers, MES cells expressing only mesenchymal markers, NEG cells negative for all of the tested markers, CNS central nervous system, HER2 human epidermal growth factor receptor 2

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