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Table 1 Patient and tumor characteristics of included cohorts

From: An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells

Characteristic Discovery cohort (n) Validation cohort (n)
Total number of samples 188 669
 Unique patients 181 666
 Primary tumors 183 665
 Recurrent tumors 5 4
Median age, years 48 58
Estrogen receptor status
 Positive 97 474
 Negative 77 142
Tumor size
 T1 66 176
 T2 81 371
 T3 5 86
Node status
 Positive 59 356
 Negative 91 290
Histological type
 Ductal 120 446
 Lobular 8 134
 Medullary 3 5
 Mixed 9 24
 Other 18 44
Molecular subtype
 Luminal A 41 251
 Luminal B 30 144
 HER2-enriched 32 73
 Basal-like 44 126
 Normal-like 11 67
  1. HER2 human epidermal growth factor receptor 2