Table 1 Patient and tumor characteristics of included cohorts
Characteristic | Discovery cohort (n) | Validation cohort (n) |
|---|---|---|
Total number of samples | 188 | 669 |
 Unique patients | 181 | 666 |
 Primary tumors | 183 | 665 |
 Recurrent tumors | 5 | 4 |
Median age, years | 48 | 58 |
Estrogen receptor status | ||
 Positive | 97 | 474 |
 Negative | 77 | 142 |
Tumor size | ||
 T1 | 66 | 176 |
 T2 | 81 | 371 |
 T3 | 5 | 86 |
Node status | ||
 Positive | 59 | 356 |
 Negative | 91 | 290 |
Histological type | ||
 Ductal | 120 | 446 |
 Lobular | 8 | 134 |
 Medullary | 3 | 5 |
 Mixed | 9 | 24 |
 Other | 18 | 44 |
Molecular subtype | ||
 Luminal A | 41 | 251 |
 Luminal B | 30 | 144 |
 HER2-enriched | 32 | 73 |
 Basal-like | 44 | 126 |
 Normal-like | 11 | 67 |