Fig. 5
From: The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
Effect of Agelastatin A treatment of co-cultured breast cancer cells on development of lung metastases in a mouse xenograft model. Percent of xenograft-bearing mice with indicated degree of detectable lung metastases after implantation with SUM1315 breast cancer cells isolated from co-cultures with indicated fibroblasts and incorporation of AgelA or MeOH at equivalent dilution in the cultures. Mean tumor weights +/- standard deviation (SD) are indicated for each cohort. * = p < 0.5 by Fisher’s exact test