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Fig. 5 | Breast Cancer Research

Fig. 5

From: Antitumor activity of Cetuximab in combination with Ixabepilone on triple negative breast cancer stem cells

Fig. 5

FACS analysis and mammosphere-forming efficiency in MDA-MB-231 or SUM159 xenografts. Representative results of CD44+/CD24-/low population (%) in MDA-MB-231 xenografts (a), Aldefluor + population (%) in SUM159 xenografts (b), mammosphere formation (%) in MDA-MB-231 xenografts (c), or mammosphere formation (%) in SUM159 xenografts (d). CD44+/CD24-/low population (%) and mammosphere formation (%) of MDA-MB-231 xenografts were reduced by Cetuximab alone or combination treatment. Aldefluor + population (%) in SUM159 xenografts decreased by combination treatment when compared to control. CD44+/CD24- cells (%) in SUM159 xenografts were extremely low in proportion and are not represented in the figure. N.S. not significant

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