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Table 1 Characteristics of the case and control samples

From: Mammographic density defined by higher than conventional brightness threshold better predicts breast cancer risk for full-field digital mammograms

 

Cases (n = 213) mean (SD)

Controls (n = 630) mean (SD)

P a

Age at mammogram (years)

51.6 (7.6)

51.5 (7.4)

0.9

Body mass index (kg/m2)

22.5 (2.7)

22.6 (2.8)

0.8

Age at menarche (years)

14.6 (1.6)

14.6 (1.6)

0.9

Number of live birth (per child)

2.11 (0.75)

2.27 (0.91)

0.02

Menopausal status (n, %)

  

0.9

 Premenopausal

134 (62.9)

395 (62.7)

 

 Postmenopausal

79 (37.1)

235 (37.3)

 

Benign breast lump (n, %)

  

<0.0001

 Yes

34 (16.0)

36 (5.6)

 

 No

179 (84.0)

594 (94.4)

 

Ever smoking (n, %)

  

0.08

 Yes

17 (8.0)

30 (4.8)

 

 Never

196 (92.0)

600 (95.2)

 

Ever alcohol consumption (n, %)

  

0.04

 Yes

95 (44.6)

232 (36.8)

 

 Never

118 (55.4)

398 (63.2)

 

Physical exercise (n, %)

  

0.2

 More and equal 90 mins per week

85 (39.9)

223 (35.4)

 

 Less than 90 mins per week

128 (60.1)

407 (64.6)

 

Ever use of hormonal therapy (n, %)

  

0.3

 Yes

33 (15.5)

82 (13.0)

 

 Never

180 (84.5)

548 (87.0)

 

Mammographic measurements

Cumulus

  Dense area (cm2)

18.1 (14.9)

15.6 (11.7)

0.01

  Non-dense area (cm2)

84.3 (36.0)

85.3 (34.2)

0.7

  Percentage dense area

18.6 (12.3)

16.2 (10.3)

0.006

  Total area (cm2)

102.3 (37.3)

100.9 (35.0)

0.6

  Density thresholds (0 to 4095)

2174 (355)

2142 (343)

0.2

Altocumulus

  Dense area (cm2)

14.3 (11.6)

11.4 (8.4)

0.0002

  Non-dense area (cm2)

85.0 (35.3)

87.5 (34.7)

0.4

  Percentage dense area

15.3 (10.8)

12.4 (8.5)

0.0001

  Total area (cm2)

99.2 (36.2)

99.0 (34.8)

0.9

  Density thresholds (0 to 4095)

2247 (301)

2252 (300)

0.8

Cirrocumulus

  Dense area (cm2)

3.5 (3.4)

3.0 (2.3)

0.03

  Non-dense area (cm2)

98.1 (41.0)

97.7 (38.8)

0.9

  Percentage dense area

3.8 (2.8)

3.3 (2.4)

0.03

  Total area (cm2)

101.6 (41.4)

100.8 (39.0)

0.8

  Density thresholds (0 to 4095)

2559 (205)

2574 (226)

0.4

  1. SD standard deviation
  2. a P refers to statistical significance for the discrimination between cases and controls