Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet

Breast Cancer Research

Table 5 Effect of diet alone vs diet + DMBA on gene expression at 13 weeks old

		Fold regulation (compared with LFD)
Symbol	Description	HFD + DMBA	HFD alone
Tgfa	Transforming growth factor alpha	2.4	NS
Ccl1	Chemokine (C-C motif) ligand 1	3.8	NS
Ccl17	Chemokine (C-C motif) ligand 17	2.8	NS
Ccl20	Chemokine (C-C motif) ligand 20	11	NS
Ccl22	Chemokine (C-C motif) ligand 22	4	NS
Tgfb1	Transforming growth factor, β1	1.6	NS

DMBA 7,12-dimethylbenz[a]anthracene, HFD high saturated animal fat diet, LFD low-fat diet
p < 0.05 for all genes listed, except NS = no significant change (n = 4 mice per diet treatment)

ISSN: 1465-542X