Table 2 CD68+ and CD163+ cell number median values and relevant clinical characteristics
From: Human breast cancer cells educate macrophages toward the M2 activation status
Factor | N = 551 | CD68+ median (range) | P a | N = 537 | CD163+ median (range) | P a | ||
|---|---|---|---|---|---|---|---|---|
Histological type | ||||||||
Ductal | 392 | 418 | (0–3634) | 384 | 208 | (2–1772) | ||
Lobular | 109 | 249 | (1–3113) | 102 | 106 | (3–802) | ||
Other | 50 | 265 | (0–1397) | <0.001 | 51 | 127 | (4–1359) | <0.001 |
Histological grade | ||||||||
Grade 1 | 46 | 240 | (18–3113) | 42 | 125 | (5–524) | ||
Grade 2 | 257 | 337 | (0–3634) | 250 | 115 | (2–1229) | ||
Grade 3 | 246 | 436 | (0–2595) | <0.001 | 243 | 265 | (3–1772) | <0.001 |
N.A. | 2 | 2 | ||||||
ER status | ||||||||
Positive | 396 | 340 | (0–3634) | 385 | 131 | (2–1772) | ||
Negative | 155 | 435 | (0–2595) | 0.006 | 152 | 268 | (6–1743) | <0.001 |
HER-2 status | ||||||||
Positive | 168 | 363 | (9–2673) | 165 | 221 | (2–1772) | ||
Negative | 383 | 369 | (0–3634) | 0.900 | 372 | 148 | (3–1359) | 0.002 |
Biological group | ||||||||
ER+, HER-2− | 307 | 334 | (0–3634) | 296 | 124 | (3–1359) | ||
ER+, HER-2+ | 89 | 343 | (12–2673) | 89 | 200 | (2–1772) | ||
ER-, HER-2+ | 79 | 424 | (9–1306.5) | 76 | 227 | (7–1743) | ||
ER-, HER-2− | 76 | 484 | (0–2595) | 0.023 | 76 | 289 | (6–1111) | <0.001 |
Ki67 | ||||||||
≤20 % | 265 | 318 | (0–3634) | 254 | 115 | (2–1772) | ||
>20 % | 238 | 431 | (0–2794) | 0.002 | 236 | 263 | (3–1743) | <0.001 |
N.A. | 48 | 47 | ||||||