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Table 2 CD68+ and CD163+ cell number median values and relevant clinical characteristics

From: Human breast cancer cells educate macrophages toward the M2 activation status

Factor N = 551 CD68+ median (range) P a N = 537 CD163+ median (range) P a
Histological type       
Ductal 392 418 (0–3634)   384 208 (2–1772)  
Lobular 109 249 (1–3113)   102 106 (3–802)  
Other 50 265 (0–1397) <0.001 51 127 (4–1359) <0.001
Histological grade         
Grade 1 46 240 (18–3113)   42 125 (5–524)  
Grade 2 257 337 (0–3634)   250 115 (2–1229)  
Grade 3 246 436 (0–2595) <0.001 243 265 (3–1772) <0.001
N.A. 2     2    
ER status         
Positive 396 340 (0–3634)   385 131 (2–1772)  
Negative 155 435 (0–2595) 0.006 152 268 (6–1743) <0.001
HER-2 status         
Positive 168 363 (9–2673)   165 221 (2–1772)  
Negative 383 369 (0–3634) 0.900 372 148 (3–1359) 0.002
Biological group         
ER+, HER-2− 307 334 (0–3634)   296 124 (3–1359)  
ER+, HER-2+ 89 343 (12–2673)   89 200 (2–1772)  
ER-, HER-2+ 79 424 (9–1306.5)   76 227 (7–1743)  
ER-, HER-2− 76 484 (0–2595) 0.023 76 289 (6–1111) <0.001
Ki67         
≤20 % 265 318 (0–3634)   254 115 (2–1772)  
>20 % 238 431 (0–2794) 0.002 236 263 (3–1743) <0.001
N.A. 48     47    
  1. aMann-Whitney or Kruskal-Wallis test. ER estrogen receptor, HER-2 human epidermal growth factor receptor 2, N.A. not available