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Fig. 2 | Breast Cancer Research

Fig. 2

From: Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence

Fig. 2

Protein expression profiling of eight commonly used human breast cell lines. Receptor levels and signalling molecules downstream of the insulin receptor/insulin-like growth factor-1 receptor (INSR/IGF1R) signalling pathway have been quantified. Furthermore some breast cancer subtype markers have been used to further characterize these cell lines that are commonly used in the research articles discussed in this review. Her2 human epidermal growth factor receptor 2, EGFR epidermal growth factor receptor, ER oestrogen receptor, PR progesterone receptor, Erk extracellular signal-related kinase, GAPDH glyceraldehyde-3-phosphate dehydrogenase IRS Insulin Receptor Substrate

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