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Fig. 2 | Breast Cancer Research

Fig. 2

From: Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells

Fig. 2

Experimental setup of microarray experiment. a Two-dimensional principal component analysis plot of the microarray gene expression data. A clear separation of the different treatments (indicated by the different colors of the dots), cell lines (different shapes) and time points (light; 1 h vs. dark; 6 h) could be observed. The triplicates or quadruplicates are as expected very close to each other. b Number of significantly differentially expressed genes between the different cell lines at T = 1 h. The first Venn diagram shows overlap of the significant differentially expressed genes (DEGs) per cell line at T = 1 h. The second Venn diagram shows overlap of the significant DEGs per treatment at T = 1. c As in (b) but then for T = 6 h

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