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Fig. 3 | Breast Cancer Research

Fig. 3

From: Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response

Fig. 3

Association of changes in gene expression between pretreatment and residual tumors (TS − T1) and recurrence-free survival (RFS). a Scatterplot showing the expression of a representative interferon signaling gene, IFIH1, at TS and T1, with the color of the points indicating outcome (red = no recurrence; blue = recurrence). The diagonal line represents no change in gene expression levels (T1 = TS). The length of the vertical lines between points and the diagonal line represents the magnitude of expression change from T1 to TS. Kaplan-Meier analysis of RFS among patients with high (top tertile: blue) or low expression (red) levels of IFIH1 at T1 (b), at TS (c) and the change in gene expression between two time points (TS − T1) (d)

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Breast Cancer Research

ISSN: 1465-542X

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