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Table 1 Correlation between rKi67 and various relative DOT parameters

From: Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures

Analysis of correlation with rKi67 % rStO2 rTHC rHbO2 rHb s
Pearson’s correlation coefficient 0.89 0.55 0.68 −0.33 0.44
P-value 0.001 0.126 0.044 0.393 0.24
Spearman’s correlation coefficient 0.88 0.40 0.48 −0.43 0.35
P-value 0.003 0.291 0.194 0.250 0.359
  1. Relative tissue oxygen saturation (rStO2) and relative oxyhemoglobin concentration (rHbO2) were highly correlated with rKi67. Results with statistical significance (p-value <0.05) are shown in bold (n = 9). rTHC denotes relative total hemoglobin concentration, rHb denotes relative deoxyhemoglobin concentration, and rμs' denotes relative reduced-scattering coefficients