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Fig. 2 | Breast Cancer Research

Fig. 2

From: Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers

Fig. 2

Manhattan plot of the P value profiles of paired Student’s t test comparing the pre-RRSO and post-RRSO measures of background parenchymal enhancement (BPE) (both |BPE| and BPE %) computed by using a range of values (from 0 % to 100 %) for the R %cutoff, indicating a range of the R %cutoff values on which the difference between the pre-RRSO and post-RRSO BPE measures become significant (P < 0.05). RRSO, Risk-reducing salpingo-oophorectomy. a Results for the full cohort (i.e., a total of 50 women). b Results for the 44 women who did not develop breast cancer post-RRSO. c Results for the 6 women who developed breast cancer post-RRSO. Abbreviation: SUB, Subtraction image (i.e., post-contrast minus pre-contrast)

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